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1

HISTONE DEACETYLASES AND CANCER: CAUSES AND THERAPIES

Marks, Paul A., Rifkind, Richard A., Richon, Victoria M., Breslow, Ronald, Miller, Thomas, Kelly, William K.

Journal:

Nature Reviews Cancer

Year:

2001

Language:

english

File:

PDF, 623 KB

english, 2001

2

10.1038/43710

Pavletich, Nikola P., Finnin, Michael S., Donigian, Jill R., Cohen, Alona, Richon, Victoria M., Rifkind, Richard A., Marks, Paul A., Breslow, Ronald

Journal:

Year:

1999

Language:

english

File:

PDF, 448 KB

english, 1999

3

Heparin-binding growth factor isolated from human prostatic extracts

Jack H. Mydlo, Muhammad A. Bulbul, Victoria M. Richon, Warren D. W. Heston, William R. Fair

Journal:

Year:

1988

Language:

english

File:

PDF, 699 KB

english, 1988

4

Vorinostat in solid and hematologic malignancies

David Siegel, Mohamad Hussein, Chandra Belani, Francisco Robert, Evanthia Galanis, Victoria M Richon, José Garcia-Vargas, Cesar Sanz-Rodriguez, Syed Rizvi

Journal:

Journal of Hematology & Oncology

Year:

2009

Language:

english

File:

PDF, 969 KB

english, 2009

5

Histone Deacetylase Inhibitors: Development of Suberoylanilide Hydroxamic Acid (SAHA) for the Treatment of Cancers

Victoria M. Richon, Xianbo Zhou, Richard A. Rifkind, Paul A. Marks

Journal:

Blood Cells, Molecules, and Diseases

Year:

2001

Language:

english

File:

PDF, 39 KB

english, 2001

6

The importance of being Me: Magic methyls, methyltransferase inhibitors and the discovery of tazemetostat.

Kuntz, Kevin W, Campbell, John Emmerson, Keilhack, Heike, Pollock, Roy M, Knutson, Sarah K, Porter Scott, Margaret, Richon, Victoria M, Sneeringer, Chris J, Wigle, Tim J, Allain, Christina J, Majer, C

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 468 KB

english, 2016

7

Hybrid polar inducers of transformed cell differentiation/apoptosis. From the cell to the clinic

Paul A Marks, Victoria M Richon, Ronald Breslow, Richard A Rifkind

Journal:

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie

Year:

1999

Language:

english

File:

PDF, 567 KB

english, 1999

8

P51. Defining the apoptotic pathways underlying histone deacetylase inhibitor-mediated tumor therapy

Ralph K. Lindemann, Andrea Newbold, Kate Whitecross, Anthony E. Dear, Clare L. Scott, Andrew Wei, Victoria Richon, Scott W. Lowe, Ricky W. Johnstone

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 64 KB

english, 2006

9

Inducing Differentiation of Transformed Cells with Hybrid Polar Compounds: A Cell Cycle-Dependent Process

Paul A. Marks, Victoria M. Richon, Hiroaki Kiyokawa and Richard A. Rifkind

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 910 KB

english, 1994

10

A687V EZH2 is a gain-of-function mutation found in lymphoma patients

Christina R. Majer, Lei Jin, Margaret Porter Scott, Sarah K. Knutson, Kevin W. Kuntz, Heike Keilhack, Jesse J. Smith, Mikel P. Moyer, Victoria M. Richon, Robert A. Copeland, Tim J. Wigle

Journal:

Year:

2012

Language:

english

File:

PDF, 448 KB

english, 2012

11

Epigenetic approaches to cancer therapy

Roy M. Pollock, Victoria M. Richon

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2009

Language:

english

File:

PDF, 326 KB

english, 2009

12

Targeting histone deacetylases: development of vorinostat for the treatment of cancer

Richon, Victoria M

Journal:

Year:

2010

Language:

english

File:

PDF, 956 KB

english, 2010

13

Aminosuberoyl hydroxamic acids (ASHAs): A potent new class of HDAC inhibitors

Sandro Belvedere, David J. Witter, Jiaming Yan, J. Paul Secrist, Victoria Richon, Thomas A. Miller

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 122 KB

english, 2007

14

Induced differentiation, the cell cycle, and the treatment of cancer

Richard A. Rifkind, Victoria M. Richon, Paul A. Marks

Journal:

Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 815 KB

english, 1996

15

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

Christopher J. Sneeringer, Margaret Porter Scott, Kevin W. Kuntz, Sarah K. Knutson, Roy M. Pollock, Victoria M. Richon, Robert A. Copeland and James A. Wells

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.43 MB

english, 2010

16

Structural Approaches to Cancer Drug Development

Chabner, Bruce, Richon, Victoria

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 500 KB

english, 2015

17

The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states

Tim J. Wigle, Sarah K. Knutson, Lei Jin, Kevin W. Kuntz, Roy M. Pollock, Victoria M. Richon, Robert A. Copeland, Margaret Porter Scott

Journal:

Year:

2011

Language:

english

File:

PDF, 476 KB

english, 2011

18

Chemogenetic Analysis of Human Protein Methyltransferases

Victoria M. Richon, Danielle Johnston, Christopher J. Sneeringer, Lei Jin, Christina R. Majer, Keith Elliston, L. Fred Jerva, Margaret Porter Scott, Robert A. Copeland

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

19

A new path to the cancer epigenome

Richon, Victoria M

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 264 KB

english, 2008

20

[Methods in Enzymology] Chromatin and Chromatin Remodeling Enzymes, Part B Volume 376 || Histone Deacetylase Inhibitors: Assays to Assess Effectiveness In Vitro and In Vivo

Richon, Victoria M

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

21

Histone deacetylase inhibitors and retinoic acids inhibit growth of human neuroblastoma in vitro

Dennis C. Coffey, Martha C. Kutko, Richard D. Glick, Steven L. Swendeman, Lisa Butler, Richard Rifkind, Paul A. Marks, Victoria M. Richon, Michael P. LaQuaglia

Journal:

Pediatric Blood & Cancer

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

22

TNFα Disrupts Mitotic Clonal Expansion and Regulation of Retinoblastoma Proteins p130 and p107 during 3T3-L1 Adipocyte Differentiation

Robert E. Lyle, Victoria M. Richon, Robert E. McGehee Jr.

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 414 KB

english, 1998

23

Hexamethylenebisacetamide-Induced Erythroleukemia Cell Differentiation Involves Modulation of Events Required for Cell Cycle Progression through G1

Hiroaki Kiyokawa, Victoria M. Richon, Gisela Venta-Perez, Richard A. Rifkind and Paul A. Marks

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.08 MB

english, 1993

24

Histone deacetylases

Paul A Marks, Thomas Miller, Victoria M Richon

Journal:

Current Opinion in Pharmacology

Year:

2003

Language:

english

File:

PDF, 189 KB

english, 2003

25

Selective Induction of Apoptosis by Histone Deacetylase Inhibitor SAHA in Cutaneous T-Cell Lymphoma Cells: Relevance to Mechanism of Therapeutic Action

Zhang, Chunlei, Richon, Victoria, Ni, Xiao, Talpur, Rakhshandra, Duvic, Madeleine

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 441 KB

english, 2005

26

Development of vorinostat: Current applications and future perspectives for cancer therapy

Victoria M. Richon, Jose Garcia-Vargas, James S. Hardwick

Journal:

Year:

2009

Language:

english

File:

PDF, 288 KB

english, 2009

27

Induced differentiation of cancer cells: Second generation potent hybrid polar compounds target cell cycle regulators

Paul A. Marks, Victoria M. Richon, Richard A. Rifkind

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1996

Language:

english

File:

PDF, 114 KB

english, 1996

28

Cloning of the cDNA encoding phenylalanyl tRNA synthetase regulatory α-subunit-like protein whose expression is down-regulated during differentiation

Xianbo Zhou, Victoria M. Richon, Lang Ngo, Richard A. Rifkind, Paul A. Marks

Journal:

Year:

1999

Language:

english

File:

PDF, 526 KB

english, 1999

29

Evidence for Microheterogeneity in the Structure of Human Glucocorticoid Receptors*

CIDLOWSKI, JOHN A., RICHON, VICTORIA

Journal:

Year:

1984

Language:

english

File:

PDF, 1.40 MB

english, 1984

30

Histone deacetylase inhibitors as new cancer drugs

Marks, Paul A., Richon, Victoria M., Breslow, Ronald, Rifkind, Richard A.

Journal:

Current Opinion in Oncology

Year:

2001

Language:

english

File:

PDF, 1.10 MB

english, 2001

31

Protein methyltransferases as a target class for drug discovery

Copeland, Robert A., Solomon, Michael E., Richon, Victoria M.

Journal:

Nature Reviews Drug Discovery

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

32

MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

Kathrin M. Bernt, Nan Zhu, Amit U. Sinha, Sridhar Vempati, Joerg Faber, Andrei V. Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger, Roy M. Pollock, Victoria M. Richon, Andrew L. Kun

Journal:

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

33

A Class of Hybrid Polar Inducers of Transformed Cell Differentiation Inhibits Histone Deacetylases

Victoria M. Richon, Stephane Emiliani, Eric Verdin, Yael Webb, Ronald Breslow, Richard A. Rifkind and Paul A. Marks

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.20 MB

english, 1998

34

Chabner Colloquium: Answering the Big Questions in Cancer Research & 2018 STO Annual MeetingAbstract 1 – Beyond PARP1: Ribosylation as a Target for Cancer TherapyAbstract 2 – Melanoma: Clues to Improved Therapeutic Efficacy from Disease PathogenesisAbstract 3 – Targeting Cell Death Pathways with Precision Using Functional AssaysAbstract 4 – Digital RNA‐based Analysis of Circulating Tumor Cells for Noninvasive Monitoring of CancerAbstract 5 – Clinical Application of Liquid Biopsies and Genotype‐Directed Targeted Therapies for Metastatic Breast CancerAbstract 6 – Microfluidics for the Characterization of Tumor‐Specific Extracellular VesiclesAbstract 7 – CAR T‐Cell Therapy for Ovarian CancerAbstract 8 – Molecular Tumor Board: Resistance to Che

Richon, Victoria, Fisher, David E., Letai, Anthony, Haber, Daniel A., Bardia, Aditya, Stott, Shannon, Yeku, Oladapo, Sullivan, Ryan, Liu, David, Spring, Laura, Dagogo‐Jack, Ibiayi, Nagayama, Aiko, Fra

Journal:

Year:

2018

Language:

english

File:

PDF, 5.93 MB

english, 2018

35

Sequence-specific potentiation of topoisomerase II inhibitors by the histone deacetylase inhibitor suberoylanilide hydroxamic acid

Douglas C. Marchion, Elona Bicaku, Adil I. Daud, Victoria Richon, Daniel M. Sullivan, Pamela N. Munster

Journal:

Journal of Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 469 KB

english, 2004

36

Characteristics of Erythroleukemia Cells Selected for Vincristine Resistance That Have Accelerated Inducer-Mediated Differentiation

Victoria M. Richon, Nadine Weich, Lin Leng, Hiroaki Kiyokawa, Lang Ngo, Richard A. Rifkind and Paul A. Marks

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 964 KB

english, 1991

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